Antisoma zu alten Höhen ?
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Das alte Hoch war bei 0,70.
Da ist mächtig Bewegung drin.
Wenn die erst starten hoffen wir wohl auf weitaus höhere Kurse.
Börse-Online hat den Wert ja mal vor 3 oder 4 Monaten empfohlen.
Zwischendurch gab es Ernüchterung, was den Kursverlauf angeht, aber momentan sieht es so aus, als ob das Vertrauen stark ist, daß man hier bald richtig Geld verdienen wird.
sehen sie das aber nicht so rosig!
Akt. Kurs | 35,38 |
Diff. abs. | -1,13 |
Diff. % | -3,08 |
Zeit | 09:02 |
Datum | 12.10.09 |
Eröffnung | 36,50 |
Vortagesschluss | 36,50 |
Tageshoch | 36,50 |
Tagestief | 35,38 |
Volumen (in GBX) | 1.357.200 |
geh. Stück | 37.800 |
52 W-Hoch | 38,50 |
52 W-Tief | 17,25 |
Insider haben auch eingekauft. Abwarten.
Mfg
Kalle
October 2009 – Antisoma plc (LSE: ASM; USOTC: ATSMY) announces that its aptamer drug AS1411 has been granted orphan drug status in both the United States and the European Union for the treatment of acute myeloid leukaemia (AML). The grants will provide seven years of market exclusivity in the US and ten years of exclusivity in the EU if AS1411 is approved for use in AML. Positive phase II data for AS1411 in AML were presented at the 2008 ASH and 2009 ASCO meetings. Addition of AS1411 to high-dose cytarabine increased response rates without significantly increasing side-effects in patients with relapsed or refractory AML. Phase IIb trials are now planned: the first is expected to start in early 2010. Should this yield positive findings, rapid progress into a registration trial is anticipated. AS1411 already has orphan drug status in both the US and the EU for the treatment of renal cancer. A phase II trial in renal cancer is ongoing, and expected to report initial data before the end of this year. Glyn Edwards, Antisoma's CEO, said: "Gaining orphan drug status in AML further strengthens the exclusivity position of AS1411 in a setting where we have positive phase II data. This is an exciting time for AS1411 , with phase II data in renal cancer coming soon and our investigation of the compound in AML progressing to the next stage." Enquiries: Antisoma plc Glyn Edwards, CEO Daniel Elger, VP Marketing & Communications + 44 (0) 7909 915 068 Buchanan Communications (media enquiries) Mark Court/Lisa Baderoon/Catherine Breen + 44 (0)20 7466 5000 The Trout Group (US investor enquiries) Seth Lewis + 1 617 583 1308 Except for the historical information presented, certain matters discussed in this announcement are
Meine unbedeutende Meinung!
Alternative: Antisoma ist einfach nicht mehr wert als 40 cent!
Der Verlauf der letzten 4 Wochen war ja eigentlich sehr gut und irgendwann knallt hier auch der Korken!
has the potential to work in settings where other treatments provide limited benefit. We are developing AS1413 initially as a treatment for secondary acute myeloid leukaemia (secondary AML), a form of AML that evolves from prior bone marrow disease or develops following radiotherapy or chemotherapy for other cancers. Patients with secondary AML often have multi-drug resistant disease and there are no drugs approved specifically for this condition. We are enrolling patients into a pivotal, randomised phase III trial of AS1413 in secondary AML. This trial, called ACCEDE, compares AS1413 plus cytarabine with daunorubicin plus cytarabine, the most common initial treatment for AML. The ACCEDE study builds on positive data from previous studies: from a phase I trial, just published in Leukemia Research , which highlighted the drug's potential in this setting, and from a phase II trial that evaluated the drug in 88 patients with secondary AML. Final follow-up data from the phase II trial will be presented at this year's ASH meeting in December. Results from the ACCEDE trial are expected to be available in late 2010 or early 2011. Should these be positive, we plan to market the drug ourselves in the US while seeking partners for marketing in other territories. We believe that AS1413 could achieve worldwide sales running into hundreds of millions of dollars as a treatment for secondary AML, and that there is also a wider opportunity for the drug in other blood cancer settings. AS1411 – significant developments ahead Earlier this year we presented positive data from a phase II trial of our aptamer drug, AS1411 , in AML. The addition of 10 or 40
mg/kg/day AS1411 to cytarabine chemotherapy increased the response rate without significantly increasing side-effects. We now plan to build on these findings by conducting a phase IIb trial, which is expected to begin early next year. The new trial will include around 90 patients in three treatment groups: a control group will get chemotherapy alone while two combination groups receive AS1411 together with chemotherapy. AS1411 will be given at 40 or 80 mg/kg/day, so the highest dose tested will be twice that used in the previous trial. The dose of cytarabine chemotherapy will also be slightly higher than that used previously. In addition, the patient population will be refined: the prior trial included patients who had proved unresponsive (refractory) to previous therapy or who had suffered up to three relapses, whereas the new trial will only include patients in first relapse or refractory to one previous treatment. The phase IIb trial will capture the initial response to treatment, how long patients remain disease-free and how long they survive following treatment. The goal is to provide a data-set that allows us to make optimal plans for a registration study. In parallel with the programme in AML, we have been running a single-arm phase II trial in renal cancer. This completed patient enrolment in May, and is expected to report initial data before the end of 2009. As with AS1413 , Antisoma currently retains all marketing and commercialisation rights to AS1411. We plan to continue development through late-stage trials and to commercialise the product ourselves in the US while seeking partners for other territories. Strong financial position We reported in our year-end financial results that we had GBP 67.0
million at the end of June 2009 , and indicated that these funds were sufficient to support all our priority programmes until mid-2011 , beyond the time when data are expected from the key phase III studies of ASA404 and AS1413. Outlook Before the end of this year, we expect the first data from our phase II trial of AS1411 in renal cancer and additional details of Novartis' plans for developing ASA404 in breast cancer. We are moving forward with our plans to transition from a company focused on developing cancer drugs into one that can also successfully commercialise them. While our principal focus is the completion of phase III trials on ASA404 and AS1413 , we also continue to advance the earlier stage products in our portfolio and to explore opportunities to add new drugs to the pipeline. Enquiries : Antisoma plc + 44 (0)203 249 2100 / + 44 (0) 7909 915068 Glyn Edwards, Chief Executive Officer Daniel Elger, VP, Marketing & Communications Alison Saville, Senior Marketing & Communications Executive
Mfg
Kalle
Healthcare
* Has no revenue in H1
* Shares down 1.4 pct (Adds details)
Feb 18 (Reuters) - British cancer specialist Antisoma's (ASM.L) first-half pretax loss tripled as the company had no revenue during the period and operating costs increased 6.8 percent.
Antisoma said it would not pursue further development of its mid-stage drug candidate, AS1411, for renal cancer because of the "highly competitive nature of the renal cancer market."
The company said it would focus on developing the drug for the acute myeloid leukaemia (AML) indication instead.
AS1411 has already received an orphan drug status in the United States and the European Union for the AML indication.
http://www.reuters.com/article/idUSSGE61H0AR20100218
3:21 a.m. Today 3:21 a.m. March 29, 2010
Antisoma halts lung cancer treatment trial
2:27 a.m. Today 2:27 a.m. March 29, 2010
Biopharmaceutical firm Antisoma (UK:ASM 9.90, -22.10, -69.06%) said Monday that interim analysis of data from the ATTRACT-1 phase III trial of ASA404 in previously untreated non-small cell lung cancer has shown that continuation of the trial would be futile. The firm said that the trial showed there is little or no prospect of demonstrating a survival benefit with ASA404 in this setting. The ATTRACT-1 trial will therefore be halted
Hab meine Position verdoppelt.
Kann in Nachhinein Blödsinn
gewesen sein, aber vielleicht
auch mutig und weise.
Fortes fortuna adjuvat.
Gruß
sertralin19
Es sind doch noch mehrere erfolgsversprechende Kanditaten in der Pipeline!
vermutlich wird die Tage eine Gegegbewegung kommen!
Cash ist da, Projekte auch.
Und mit Novartis ein starker Partner,
der selbst Anteile an Antisoma hält.
Antisoma hat schon so viele
Krisen ausgestanden, da seh
ich nicht gleich den Weltuntergang
wegen einer weiteren Pleitestudie.
Irgendwann wird ein Kandidat
den Markt erreichen.
Steter Tropfen hölt den Stein.
Das kann natürlich dauern.
Und der Kurs war immer für
extreme Schwankungen gut.
Aber wer ernsthaft in solche
Werte investiert, bringt für
gewöhnlich ja Zeit mit.
Sonst würde ich auch die
Finger davon lassen.
LG
sertralin19